MELANOTAN-1 (10mg) - stimulation of melanin synthesis

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MELANOTAN-1 is very similar to naturally occurring alpha melanocyte stimulating hormone alpha-MSH (Melanotan 2). Alpha-MSH is primarily known for its influence on melanocytes, the cells in skin and hair responsible for pigmentation. This function is mediated via strong binding to melanocortin receptor 1. Alpha-MSH is a non-selective full agonist of melanocortin receptors 1, 3, 4, and 5. Melanotan 1 differs from alpha-MSH (Melanotan 2) by a single amino acid and was actually first developed as a sunless tanning agent. Research into melanocortin receptors and their effects was relatively limited at the time and scientists quickly discovered that while melanotan 1 did indeed cause pigmentation, it also increases sexual arousal, boosted appetite, and altered baseline metabolism. Subsequent study of melanotan 1 and other melanocortin-binding proteins helped scientists to better understand the melanocortin signaling system.

This peptide was discovered at the University of Arizona as a result of the study of substances that can stimulate the production of melanin in the skin. The skin pigment melanin is a natural defense against UV rays, which are known to be one of the risk factors for skin cancer, melanoma. The action of melanotan I is to launch a cascade of biochemical reactions and activate physiological pathways for the synthesis of melanin in the epidermal layer.

It is used clinically, in Europe, to prevent sun-related skin damage (i.e. phototoxicity) from occurring in people suffering from erythropoietic protoporphyria. The peptide is in phase 3 clinical trials for the treatment of polymorphose light eruption and is in phase 2 clinical trials for the treatment of actinic keratosis (a specific type of skin damage caused by the sun) and its more serious counterpart, squamous cell carcinoma.

Quantity: 10 mg

Purity: over 97%

Form: lyophilizate

Excipient: mannitol

Storage: no more than +5C

Amino acid sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2

Molecular weight: 1646.85

Molecular formula: C₇₈H₁₁₁N₂₁O₁₉

Synonyms: Melanotan-I, MT-1, MT-I, Меланотан, Меланотан-1, Меланотан-I, NDP-MSH, Melanotan Ⅰ, MELANOTAN I, Melanotan-1, Melanotropin, Afamelanotide, Афамеланотид, [Nle4,D-Phe7]α-MSH, Melanotan Ⅰ Acetate;Melanotan ① Acetate, [Nle4]-α-MSH, amide

Main area of research: stimulation of melanin synthesis

Structural formula:

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Method of application:

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100% original product from RUSSIAN PEPTIDE (Russian Federation)

RUSSIAN PEPTIDE is a commercial, innovative technology-based organization providing a full range of services to the pharmaceutical, biotechnology and cosmetics industries.
The company specializes in the development of technology and production of peptides and complex organic molecules as biologically active ingredients and their intermediates, biochemical substances for in vitro research purposes, reference standards for the calibration of analytical equipment, as well as reagents for peptide synthesis.

Development and production:

RUSSIAN PEPTIDE is a commercial, innovative technology-based organization providing a full range of services to the pharmaceutical, biotechnology and cosmetics industries.