POLYOXIDONIUM 12 mg 10 tablets - immunocorrector with anti-inflammatory action

POLYOXIDONIUM (azoximer bromide) helps inhibit the progression of acute respiratory viral infections and influenza, improving overall well-being from the first day of administration through its action at viral entry sites and support in eliminating viral toxins.

Polyoxidonium® contains the active substance azoximer bromide, which belongs to the class of immunostimulatory agents.

Indications:

Treatment and prevention of acute and chronic respiratory disorders:

• Acute respiratory viral infections (ARVI) and influenza
  Inflammatory conditions of the oropharynx, paranasal sinuses, upper and lower respiratory tract, as well as the inner and middle ear
• Allergic disorders (including hay fever and bronchial asthma) complicated by recurrent bacterial, fungal, or viral infections
• Exacerbations of chronic diseases affecting the upper respiratory tract, paranasal sinuses, and chronic otitis

Advantages:

• Stimulates early anti-infective defense mechanisms by enhancing the activity of phagocytes, neutrophils, and NK cells, supporting a faster immune response to viral infections.
• Provides a pronounced detoxifying effect by binding and helping eliminate toxins and inflammatory by-products, thereby reducing symptoms associated with viral intoxication.
• When used topically, it acts directly on mucosal surfaces at the site of infection, activating local immune protection and helping limit viral spread.
• Supports reduction of inflammatory reactions by balancing the production of pro-inflammatory and anti-inflammatory cytokines.
• Well tolerated and does not cause local irritation.
• Included in the updated 2025 clinical guidelines of the Russian Ministry of Health for the management of acute respiratory viral infections and influenza in adults.
• Listed among vital and essential medicinal products.
• Sublingual tablets provide direct action on mucous membranes at the primary site of viral entry.

Action:

• Polyoxidonium® stimulates immune responses and promotes the production of endogenous interferons - proteins naturally produced by the body in response to viruses and other pathogens - helping increase resistance to viral and bacterial infections.
• Polyoxidonium® binds soluble toxic compounds and microparticles, assists in eliminating toxins and heavy metal salts, and inhibits lipid peroxidation.
• Polyoxidonium® helps regulate the balance between pro-inflammatory and anti-inflammatory immune processes.

Composition:

Active ingredient: azoximer bromide - 12 mg;
Excipients: mannitol - 3.6 mg, povidone - 2.4 mg, lactose monohydrate - 185.0 mg, potato starch - 45.0 mg, stearic acid - 2.0 mg.

Recommended treatment regimens:

Polyoxidonium tablets may be taken orally or sublingually (under the tongue) 20–30 minutes before meals.

TREATMENT FOR ADULTS OVER 18 YEARS OF AGE (SUBLINGUAL USE)

• Influenza and acute respiratory infections: 1 tablet twice daily for 7 days.
• Inflammatory diseases of the oropharynx: 1 tablet twice daily for 10 days.
• Allergic conditions (including hay fever and bronchial asthma) complicated by recurrent bacterial, fungal, or viral infections: 1 tablet twice daily for 10 days.
• Exacerbations of chronic diseases of the upper respiratory tract, paranasal sinuses, and chronic otitis: 1 tablet twice daily for 10 days.

PREVENTION FOR ADULTS OVER 18 YEARS OF AGE (SUBLINGUAL USE)

• Influenza and acute respiratory infections during the pre-epidemic period: 1 tablet daily for 10 days.
• Recurrent herpes infections of the nasal and labial areas: 1 tablet twice daily for 10 days.
• Prevention of exacerbations of chronic infections affecting the oropharynx, paranasal sinuses, upper respiratory tract, and inner or middle ear: 1 tablet daily for 10 days.
• Secondary immunodeficiency conditions associated with aging or exposure to adverse environmental factors: 1 tablet daily for 10 days.

TREATMENT FOR ADULTS OVER 18 YEARS OF AGE (ORAL ADMINISTRATION WITH WATER)

Diseases of the upper and lower respiratory tract: 1 tablet twice daily for 10 days.

Dosage form:

10 tablets, 12 mg.

Storage conditions:

Keep out of the reach and sight of children.

Do not use after the expiration date indicated on the package after the wording “Best before”.

The expiration date refers to the last day of the specified month.

Store at a temperature not exceeding 25°C. Do not freeze.

Guaranteed authenticity and quality:

100% Original from PETROVAX PHARM (Russian Federation)

PETROVAX PHARM is a pharmaceutical manufacturer specializing in innovative biopharmaceutical products.

The company focuses on developing vaccines and medications for the prevention and treatment of infectious diseases, oncology conditions, and rare disorders.

Its portfolio includes proprietary medicines and vaccines, contract manufacturing services, and dietary supplements.

Modern research and development facilities. Petrovax Pharm holds Russian and international patents for proprietary molecules and manufacturing technologies.

Advanced full-cycle pharmaceutical manufacturing compliant with EAEU and EU GMP quality standards.

More than 30 years of pharmaceutical industry experience.

Development and production:

PETROVAX PHARM