AC-SEMAX-NH2 (30mg) - modified peptide with neuroprotective, antihypoxic, antioxidant and psychostimulatory properties
30 mg, lyophilizate
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AC-SEMAX-NH2 is a synthetic derivative of adrenocorticotrophic hormone. Research suggests that it may help improve immune function, protect neurons, and improve cardiovascular function. It may also be beneficial in pain control and blood clotting.
Semax, which was developed in Russia, has been found to have benefit in the settings of stroke, cognitive impairment, dementia, and inflammation of the optic nerve. It has also been tested as a potential immune system booster and has been found to have antidepressant and anxiolytic properties as well.
Semax synthetic peptide increases the ability to learn and remember and is responsible for maintaining muscle tone. The mechanism of action of this compound is not fully known, probably due to its effect on melanocortin receptors located in the nervous system. The most important function of Semax is to stimulate the synthesis of brain-derived neurotrophic factor.
It is a peptide produced by neurons that is necessary for the functioning of the retina, cholinergic and dopaminergic neurons. The presence of this factor stimulates the development of new neural connections and prolongs the life of existing cells. It plays an important role in the formation of long-term memory and in all brain activities associated with the formation of new neurons, including learning new movements or increasing strength.
N-Acetyl Semax (amino acid sequence Ac-Met-Glu-His-Phe-Pro-Gly-Pro, Ac-Sem for short) was obtained in 2013 from its precursor (Semax) by acetylation with acetic anhydride followed by HPLC purification. Acetylation of the N-terminus of a peptide is commonly used to make the peptide look like a protein fragment, which increases its stability in the biological environment.
Changing the functional groups, acetylation of the amino group or amidation of the carbonyl group, at the terminal sites of the peptide is a common technique to increase resistance to the action of enzymes that destroy it in the body. The replacement of functional groups reduces the "recognition" of the peptide by enzymes. For example, amidated glucagon-like peptide-1 has a half-life 24% longer than its original form. Acylated peptides are also more stable. In addition, by reducing the polarity of the molecule, its lipophilicity increases and, as a result, the bioavailability of the drug.
Quantity: 10 mg
Purity: over 97%
Form: lyophilizate
Excipient: mannitol
Storage: no more than +5C
Amino acid sequence: Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH2
Molecular weight: 854,98
Molecular formula: C39H54N10O10S
Synonyms: N-Acetyl Semax Amidate, ацетил семакс амид.
Main area of research: nootropic properties, stimulation of brain-derived neurotrophic factor (BDNF), increased focus and memory.
N-Acetyl-Semax is a synthetic peptide valued for its neurogenic and neuro-restorative properties. Although approved for clinical use in Russia, it has not yet been evaluated in other countries. Studies show that it improves memory and cognitive function and is effective in diseases of the optic nerve, stroke and coronary heart disease. It can also boost immune function.
Structural formula SEMAX:
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Method of application:
The products are for professional use only. Peptide products are intended for research and scientific purposes only.
Guaranteed authenticity and quality:
100% original product from RUSSIAN PEPTIDE (Russian Federation)
RUSSIAN PEPTIDE is a commercial, innovative technology-based organization providing a full range of services to the pharmaceutical, biotechnology and cosmetics industries.
The company specializes in the development of technology and production of peptides and complex organic molecules as biologically active ingredients and their intermediates, biochemical substances for in vitro research purposes, reference standards for the calibration of analytical equipment, as well as reagents for peptide synthesis.
Development and production:
RUSSIAN PEPTIDE is a commercial, innovative technology-based organization providing a full range of services to the pharmaceutical, biotechnology and cosmetics industries.
