THYMOPENTIN (10mg) thymus polypeptide with immunomodulatory properties

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THYMOPENTIN (Thymus polypeptides) is a synthetic pentapeptide with the amino acid sequence Arg-Lys-Asp-Val-Tyr, which is the active site of the natural thymopoietin hormone with immunomodulatory properties. It is a polypeptide of the thymus (thymus gland). Thymopentin is produced mainly by epithelial cells of the thymus cortex and bone marrow; however, it is not known whether this peptide is secreted or retained in the cell.

Thymus polypeptides - thymosins - were discovered by A. L. Goldstein and A. White in 1965. In 1973, a standardized preparation suitable for clinical trials was isolated from calf thymus - thymosin fraction 5 (TF5, thymosin F5). TF5 consists of 40–50 peptide components with a molecular weight of up to 15,000 Da. A number of major peptides have been isolated from TF5 and their biological activity has been studied.

Studies in the 1980s showed that timopentin is a very well tolerated drug when used according to recommended dosing regimens. Some patients complained of drowsiness, but it is suggested that this symptom may be related to the known effect of thymopentine on neuromuscular junctions. It is also able to correct the imbalance of the immune system.

Studies show that in vivo injections of thymopentine do not cause a significant increase in the production of TNF-α and NO, and therefore do not have a toxic effect on the body.
It has also been shown that timopentin is well tolerated when taken simultaneously with various prescribed drugs, which indicates the absence of interaction of timopentin with other drugs.

Purpose: complex treatment Coronavirus, Infections, Immunity, T-cells, HIV, AIDS, interleukin-2, Hepatitis B, Carcinoma, Dermatitis, Scleroderma, Candidiasis, Periarthritis, Tendinitis, Gonarthrosis, Arthritis, Allergy, Bronchitis, Myasthenia gravis

Quantity: 10 mg

Purity: over 97%

Form: lyophilizate

Excipient: mannitol

Storage: no more than +5C

Amino acid sequence: Arg-Lys-Asp-Val-Tyr

Molecular weight: 679.78

Molecular formula: C₃₀H₄₉N₉O₉

Synonyms: Timopentin, TP5, Immunox, Mepentil, Sintomodulina, Timunox.

Main area of research: immunostimulant in complex therapy.

Structural formula:

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Method of application:

The products are for professional use only. Peptide products are intended for research and scientific purposes only.

Guaranteed authenticity and quality:

100% original product from RUSSIAN PEPTIDE (Russian Federation)

RUSSIAN PEPTIDE is a commercial, innovative technology-based organization providing a full range of services to the pharmaceutical, biotechnology and cosmetics industries.
The company specializes in the development of technology and production of peptides and complex organic molecules as biologically active ingredients and their intermediates, biochemical substances for in vitro research purposes, reference standards for the calibration of analytical equipment, as well as reagents for peptide synthesis.

Development and production:

RUSSIAN PEPTIDE is a commercial, innovative technology-based organization providing a full range of services to the pharmaceutical, biotechnology and cosmetics industries.